Related Experiment Videos
Myofibroblastoma in the Irradiated Breast
Yusuf Yagmur1, Manju L. Prasad, Michael P. Osborne
1Strang-Cornell Breast Center and the Department of Surgery, and the Division of Surgical Pathology, New York Hospital-Cornell Medical Center, New York, New York.
The Breast Journal
|May 12, 2001
Summary
A rare benign breast tumor, myofibroblastoma, developed after treatment for duct carcinoma in situ. This is the first reported case of post-radiation myofibroblastoma in the breast.
Area of Science:
- Oncology
- Pathology
- Radiotherapy
Background:
- Myofibroblastomas are benign tumors predominantly occurring in men.
- They are characterized by myofibroblasts and hyalinized collagen.
- Intraductal carcinoma in situ is a non-invasive form of breast cancer.
Purpose of the Study:
- To report the first case of myofibroblastoma arising after radiation therapy for breast cancer.
- To describe the clinical and pathological features of this rare post-treatment breast lesion.
Main Methods:
- Case report detailing a patient's history.
- Review of histopathological findings.
- Analysis of treatment history including wide excision and radiation therapy.
Main Results:
- A myofibroblastoma was identified in the breast tissue.
- The tumor developed following treatment for duct carcinoma in situ.
- This represents a novel observation of a post-radiation induced benign breast tumor.
Conclusions:
- Post-radiation myofibroblastoma of the breast is a rare entity.
- This case highlights the importance of considering benign post-treatment changes in breast imaging and pathology.
- Further research may be needed to understand the pathogenesis of radiation-induced myofibroblastomas.