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Updated: Aug 12, 2026
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Human Egg Maturity Assessment and Its Clinical Application
Published on: August 19, 2019
Potential researchable areas in ARTs--oocyte maturation and embryo development
1Institute for Research in Reproduction, Mumbai 400 012, India.
Indian Journal of Experimental Biology
|May 15, 2001
Summary
Assisted reproductive technologies (ARTs) offer hope for infertility, but low take-home baby rates necessitate research into areas like in vitro oocyte maturation and embryo cryopreservation to improve success.
Area of Science:
- Reproductive medicine and developmental biology.
Background:
- Infertility affects both sexes, with assisted reproductive technologies (ARTs) like in vitro fertilization and embryo transfer (IVF-ET) offering treatment options.
- Current ART success rates decline significantly after initial stages, resulting in low live birth rates (15-20%).
Purpose of the Study:
- To review emerging research areas in ARTs aimed at enhancing success rates.
- To discuss the clinical applications of these advancements, including in cancer patients.
Main Methods:
- Literature review of current research in ARTs.
- Focus on key areas: in vitro oocyte maturation, oocyte/embryo cryopreservation, embryo culture, and preimplantation genetic diagnosis.
Main Results:
- ARTs have improved infertility treatment, but live birth rates remain suboptimal.
- Ongoing research in oocyte maturation, cryopreservation, embryo culture, and genetic diagnosis shows promise for improving ART outcomes.
Conclusions:
- Further research and development in ARTs are crucial for increasing live birth rates.
- Advancements in ARTs have significant implications for various clinical conditions, including fertility preservation in cancer survivors.
