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Vision

Vision

Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.

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Related Experiment Video

Updated: Feb 15, 2026

Author Spotlight: Advancing Corneal Innervation Research Through Innovative Models

Author Spotlight: Advancing Corneal Innervation Research Through Innovative Models

Published on: December 8, 2023

Permeation through cornea.

M Malhotra¹, D K Majumdar

¹Department of Pharmaceutics, College of Pharmacy (University of Delhi), Pushp Vihar, Sector-III, New Delhi 110017, India.

Indian Journal of Experimental Biology

|May 15, 2001

Summary

This summary is machine-generated.

Corneal permeability is key for topical eye drug efficacy. This review covers corneal structure, drug permeation mechanisms, and factors influencing drug delivery, including enhancers.

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Last Updated: Feb 15, 2026

Author Spotlight: Advancing Corneal Innervation Research Through Innovative Models

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Published on: December 8, 2023

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Published on: August 18, 2011

Area of Science:

Ophthalmology
Pharmaceutics
Drug Delivery

Background:

Corneal permeability is a critical determinant of topical ophthalmic drug efficacy.
Understanding drug penetration is essential for developing effective eye treatments.

Purpose of the Study:

To provide an overview of corneal structure and drug permeation mechanisms.
To highlight factors influencing drug permeation through the cornea.
To discuss the role of ocular penetration enhancers.

Main Methods:

Literature review of corneal structure and drug permeation.
Analysis of physiological, physicochemical, and formulation factors.
Discussion of ocular penetration enhancers' impact.

Main Results:

Detailed overview of corneal anatomy and proposed permeation pathways.
Identification of key factors affecting drug transport across the cornea.
Exploration of strategies to enhance ocular drug penetration.

Conclusions:

Corneal drug permeability is multifactorial, influenced by drug properties, formulation, and ocular environment.
Ocular penetration enhancers show potential for improving topical drug delivery to the eye.
Further research into corneal permeation is vital for advancing ophthalmic therapies.