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Preparation and Use of HIV-1 Infected Primary CD4+ T-Cells as Target Cells in Natural Killer Cell Cytotoxic Assays
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Relationship between antibody-dependent cellular cytotoxicity, plasma HIV type 1 RNA, and CD4+ lymphocyte count

D N Forthal1, G Landucci, B Keenan

  • 1Division of Infectious Diseases, Department of Medicine, University of California, Irvine College of Medicine, Orange, California 92868, USA. dnfortha@uci.edu

AIDS Research and Human Retroviruses
|May 15, 2001
PubMed
Summary

Antibody-dependent cellular cytotoxicity (ADCC) plays a role in controlling HIV-1 infection by correlating with viral load and CD4+ cell counts. ADCC effector function and CD4+ cells are crucial for managing viremia.

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