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Related Experiment Videos

Neural prostheses.

A Prochazka1, V K Mushahwar, D B McCreery

  • 1Division of Neuroscience, University of Alberta, Edmonton, Alberta, Canada. arthurprochazka@ualberta.ca

The Journal of Physiology
|May 15, 2001
PubMed
Summary
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Neural prostheses (NPs) are vital assistive devices for spinal cord injury (SCI) rehabilitation, even with future neural regeneration. Further research is needed on their long-term nervous system interactions.

Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Rehabilitation Medicine

Background:

  • Spinal cord injury (SCI) often results in incomplete functional recovery, necessitating assistive devices.
  • Neural prostheses (NPs) are crucial for restoring lost functions through nerve stimulation.
  • Existing and emerging NPs, including spinal cord microstimulation (SCμstim), offer diverse applications.

Purpose of the Study:

  • To review the role and development of neural prostheses (NPs) in SCI rehabilitation.
  • To highlight the potential of spinal cord microstimulation (SCμstim) for restoring movement and bladder control.
  • To emphasize the need for understanding long-term neural interactions with NPs.

Main Methods:

  • Review of existing literature on neural prostheses (NPs) for various conditions.

Related Experiment Videos

  • Discussion of current NP applications in hearing, bladder control, respiration, and movement restoration.
  • Exploration of spinal cord microstimulation (SCμstim) as an emerging NP technology.

    • Main Results:

    • Over 40,000 implantable NPs have been used since 1963 for diverse functional restorations.
    • Epidural spinal cord stimulators and deep brain stimulators are standard for managing pain and motor disorders.
    • SCμstim shows promise for improving bladder-sphincter synergy, a key goal for SCI individuals.

    Conclusions:

    • Neural prostheses (NPs) will remain essential for SCI rehabilitation due to expected incomplete functional recovery.
    • Spinal cord microstimulation (SCμstim) presents a novel approach for enhancing bladder and bowel function.
    • Further physiological research is critical to understand the long-term effects of NPs on the nervous system.