Related Experiment Video
Updated: Jun 24, 2026

Investigating Tissue- and Organ-specific Phytochrome Responses using FACS-assisted Cell-type Specific Expression Profiling in Arabidopsis thaliana
Published on: May 29, 2010
Regulation of flowering in Arabidopsis by an FLC homologue
O J Ratcliffe1, G C Nadzan, T L Reuber
1Mendel Biotechnology, 21375 Cabot Boulevard, Hayward, California 94545, USA.
Abstract:
The Arabidopsis FLC gene encodes a MADS domain protein that acts as a repressor of flowering. Late-flowering vernalization-responsive ecotypes and mutants have high steady-state levels of FLC transcript, which decrease during the promotion of flowering by vernalization. Therefore, FLC has a central role in regulating the response to vernalization. We have isolated an Arabidopsis gene, MAF1, which encodes a protein that is closely related to FLC. Overexpression studies demonstrate that MAF1 produces comparable effects to FLC, and likely has a similar function in the regulation of flowering. In contrast to FLC, however, MAF1 expression shows a less clear correlation with the vernalization response. In addition, MAF1 overexpression does not influence FLC transcript levels. Thus, MAF1 likely acts downstream or independently of FLC transcription. We further report identification of a cluster of four additional FLC-like genes in the Arabidopsis genome.
Related Concept Videos
Morphogenesis
Photoreceptors and Plant Responses to Light
Biological Clocks and Seasonal Responses
Cell Signaling in Plants
Gene Regulation During Sporulation

