Genetic and environmental influences on anorexia nervosa syndromes in a population-based twin sample
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Updated: Oct 7, 2026

A Computer-Based Platform for Aiding Clinicians in Eating Disorder Analysis and Diagnosis
Published on: May 10, 2022
K L Klump1, K B Miller, P K Keel
1Department of Psychology, Michigan State University, East Lansing, USA.
Background:
Genetic and environmental influences on broadly-defined anorexia nervosa (AN) syndrome were examined in a population-based twin sample.
Methods:
AN syndrome was assessed in 672 female 17 year-old twins using structured interviews and a self-report questionnaire.
Results:
Twenty-six probands with AN syndrome were identified. Biometrical model-fitting analyses indicated that genetic and non-shared environmental factors accounted for 74% and 26% of the variance in AN syndrome, respectively.
Conclusions:
Findings support previous research indicating significant genetic and non-shared environmental influences on AN syndromes.
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