Synthesis of 17-phenyl-18,19,20-trinorprostaglandins. II. PG2 series

Preclinical evaluation of anti-inflammatory activities of the novel pyrrolopyrimidine PNU-142731A, a potential treatment for asthma.

The Journal of pharmacology and experimental therapeutics·1999

Contribution of serum protein association to discrepancy between the in vivo and in vitro UDS results for 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine (U-89843).

Mutation research·1998

PNU-107484A with alpha isoform-dependent functional changes in alpha(x)beta2gamma2 subtypes of rat recombinant GABA(A) receptors.

British journal of pharmacology·1998

Pyrrolopyrimidines: novel brain-penetrating antioxidants with neuroprotective activity in brain injury and ischemia models.

The Journal of pharmacology and experimental therapeutics·1997

Bioactivation of 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine (U-89843) to reactive intermediates that bind covalently to macromolecules and produce genotoxicity.

Chemical research in toxicology·1996

In vitro and in vivo biotransformation of 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-D]pyrimidine (U-89843) in the rat.

Drug metabolism and disposition: the biological fate of chemicals·1996

Tomoxiprole selectively inhibits cyclooxygenase-2.

Prostaglandins·1998

Urinary thromboxane B2 in cardiac transplant patients as a screening method of rejection.

Prostaglandins·1998

Occurrence of 13(S)-hydroxyoctadecadienoic acid in biological samples.

Prostaglandins·1998

Nomenclature of isoprostanes: a proposal.

Prostaglandins·1998

The isoprostanes: a perspective.

Prostaglandins·1998

Time course study for airway inflammation and responsiveness by repeated provocation of aeroantigen in guinea pigs.

Prostaglandins·1998

A High-Resolution Mass Spectrometry Workflow for Xenobiotic Metabolite Discovery and Toxicity Prioritization: Disperse Orange 61 as a Case Study.

Journal of the American Society for Mass Spectrometry·2026

Catalytic Phosphine-Enabled Direct δ-Addition of Substituted Allenoates to Nitroalkenes: A Route to 1,3-Dienes and 1,3,5-Trienes.

Organic letters·2026

One-Pot Michael Addition-Elimination Approach to 4-Carboranylcoumarin-Derived Luminescent Systems.

Organic letters·2026

Baicalin attenuates focal cerebral ischemic injury by modulation of bcl-2 family protein interactions.

Journal of veterinary science·2026

Omaveloxolone functions as a molecular crowbar-like degrader of STING to alleviate aging-related inflammation.

Nature communications·2026

Divergent Bioinspired Total Syntheses of Caryophyllene Sesquiterpenoids: Nigrosporinol Sulfoxide B, Punctaporonins C and U, and Desuccinoylpunctaporonin C.

Journal of the American Chemical Society·2026

Synthesis of 17-phenyl-18,19,20-trinorprostaglandins. II. PG2 series

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Preclinical evaluation of anti-inflammatory activities of the novel pyrrolopyrimidine PNU-142731A, a potential treatment for asthma.

Contribution of serum protein association to discrepancy between the in vivo and in vitro UDS results for 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine (U-89843).

PNU-107484A with alpha isoform-dependent functional changes in alpha(x)beta2gamma2 subtypes of rat recombinant GABA(A) receptors.

Pyrrolopyrimidines: novel brain-penetrating antioxidants with neuroprotective activity in brain injury and ischemia models.

Bioactivation of 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine (U-89843) to reactive intermediates that bind covalently to macromolecules and produce genotoxicity.

In vitro and in vivo biotransformation of 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-D]pyrimidine (U-89843) in the rat.

Tomoxiprole selectively inhibits cyclooxygenase-2.

Urinary thromboxane B2 in cardiac transplant patients as a screening method of rejection.

Occurrence of 13(S)-hydroxyoctadecadienoic acid in biological samples.

Nomenclature of isoprostanes: a proposal.

The isoprostanes: a perspective.

Time course study for airway inflammation and responsiveness by repeated provocation of aeroantigen in guinea pigs.

A High-Resolution Mass Spectrometry Workflow for Xenobiotic Metabolite Discovery and Toxicity Prioritization: Disperse Orange 61 as a Case Study.

Catalytic Phosphine-Enabled Direct δ-Addition of Substituted Allenoates to Nitroalkenes: A Route to 1,3-Dienes and 1,3,5-Trienes.

One-Pot Michael Addition-Elimination Approach to 4-Carboranylcoumarin-Derived Luminescent Systems.

Baicalin attenuates focal cerebral ischemic injury by modulation of bcl-2 family protein interactions.

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Divergent Bioinspired Total Syntheses of Caryophyllene Sesquiterpenoids: Nigrosporinol Sulfoxide B, Punctaporonins C and U, and Desuccinoylpunctaporonin C.

Synthesis of 17-phenyl-18,19,20-trinorprostaglandins. II. PG2 series

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