Related Experiment Videos
Two novel and potent 3-[(o-methoxyphenyl)piperazinylethyl]-5-phenylthien
W A Carroll1, K B Sippy, T A Esbenshade
1Abbott Laboratories, Neurological and Urological Diseases Research, Abbott Park, IL 60064-6101, USA. william.a.carroll@abbott.com
Bioorganic & Medicinal Chemistry Letters
|May 17, 2001
Abstract:
The synthesis and in vitro characterization of A-119637 and A-123189, two novel, selective and potent alpha1D antagonists, are described.
Related Concept Videos
Articles linked to this work by shared authors, journal, and citation graph.
A selective α2 B adrenoceptor agonist (A-1262543) and duloxetine modulate nociceptive neurones in the medial prefrontal cortex, but not in the spinal cord of neuropathic rats.
European journal of pain (London, England)·2014
Reactivation of an inert 15-mer antimicrobial peptide by truncation-directed i, i + 7 lactam cyclization.
Bioorganic & medicinal chemistry letters·2026
Semi-synthesis and activity study of α-mangostin ether derivatives bearing N-heterocyclic side chains as multitarget-directed ligands against AD.
Bioorganic & medicinal chemistry letters·2026
Caffeic acid phenethyl ester derivatives inhibit glyoxalase I activity and induce cell death in cultured cancer cell lines.
Bioorganic & medicinal chemistry letters·2026
Synthesis, computational and in vitro anti-tubercular activity studies of thiadiazole-linked pyridazinone derivatives.
Bioorganic & medicinal chemistry letters·2026
Design, synthesis, and evaluation of novel 5-aminolevulinic acid and 3-hydroxypyridinone conjugates for enhanced photodynamic therapy in triple-negative breast cancer.
Bioorganic & medicinal chemistry letters·2026
Synthesis and antimalarial activity of novel C30-aminated betulin derivatives.
Bioorganic & medicinal chemistry letters·2026
Antifungal activities and in silico prediction of Moringa oleifera Lam. fractions of leaves against Candida albicans.
Journal of advanced pharmaceutical technology & research·2026
Synthesis and structure-activity relationships of small-molecule 2-pyridone based CBX7 inhibitors.
RSC medicinal chemistry·2026
Fourier-transform infrared fingerprinting with chemometrics characterizes the anti-inflammatory activity of Rhizophora mucronata leaf fractions and profiles the active-fraction metabolites using liquid chromatography-high-resolution mass spectrometry analysis.
Journal of advanced pharmaceutical technology & research·2026
Predicting Antileishmanial Activity of Plant-Derived Compounds Using Random Forest Modeling.
microPublication biology·2026