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Updated: Sep 15, 2026

11:27
Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
Published on: April 29, 2014
The role of radical nephrectomy in metastatic renal cell carcinoma
1Department of Urology, Loyola University Medical Center, Maywood, IL 60153-5500, USA.
Abstract:
The role of cytoreductive surgery in patients with metastatic renal cancer remains controversial. Recent data from our Southwest Oncology Group trial suggest that cytoreduction confers an approximately 50% increase in median survival for such patients when they are treated with interferon-alfa-2b immunotherapy. The timing of cytoreduction, and in which patients it may be most applicable, are discussed herein.

