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Still's-like disease, breast prosthesis, and collagen implants
E Crétel1, M A Richard, R Jean
1Service de Médecine Interne, H pital Sainte-Marguerite, France.
Rheumatology International
|May 17, 2001
Summary
This study explores Still's disease linked to silicone and collagen implants. While steroids helped, implants remained, suggesting a complex relationship and the need for better diagnostic tools like ferritin levels.
Area of Science:
- Rheumatology
- Immunology
- Plastic Surgery
Background:
- Silicone-induced connective tissue disease is controversial.
- Still's disease is a rare systemic inflammatory disorder.
Observation:
- A case of Still's disease associated with silicone and collagen implants is presented.
- The patient showed steroid responsiveness but remained steroid-dependent even after silicone implant removal.
Findings:
- The case suggests a complex association between implants and Still's disease pathogenesis.
- Silicone-implant-associated syndrome may be misdiagnosed as Still's disease.
- Ferritinemia and its glycosylated fraction are proposed as potential discriminators.
Implications:
- Further research is needed to clarify the role of silicone and collagen implants in Still's disease.
- Distinguishing between silicone-implant-associated syndrome and Still's disease is crucial for appropriate management.