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Updated: May 19, 2026

Rapid In Situ Hybridization using Oligonucleotide Probes on Paraformaldehyde-prefixed Brain of Rats with Serotonin Syndrome
Published on: September 23, 2015
Preferred conformations of serotonin in relation to receptor sites
Abstract:
Using an empirical method, three preferred conformations for serotonin have been predicted. These three conformations corresponding to one extended form (phi equal to 80 degrees, psi equal to 180 degrees), and two folded forms (phi equals to 280 degrees, and psi equals to 100 degrees, phi equals to 100 degrees psi equals to 290 degrees). The calculated intramolecular distances in both forms agree with those obtained by the X-ray crystallography of various indoleamines. Furthermore, the dual receptor binding activity of serotonin has been explained in terms of extended and folded conformations.
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