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Updated: Aug 17, 2026

Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
Published on: June 6, 2011
[The role of pulmonary mast cells in hemorrhagic shock]
M Humeńczyk-Zybała1, I Kasacka, L Chyczewski
1Zakład Anestezjologii i Intensywnej Terapii Samodzielnego Publicznego Dzieciecego Szpitala Klinicznego Akademii Medycznej w Białymstoku.
Abstract:
In the course of hemorrhagic shock there are multidirectional organ changes that result in intensified disfunction of important organs as well as multiorgan insufficiency syndrome. The syndrome is a cause of high posthemorrhagic mortality. The general inflammatory reaction of intestine--liver--lungs--immunological system increases in a cascadical way and has a significant role in the pathogenesis of the syndrome. Mast cells activated as a result of ischemia and reprefusion participate in this phenomenon.
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