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Enantiomer separation by capillary electrophoresis utilizing noncyclic mono-, oligo- and polysaccharides as chiral
1Analytical Chemistry Department, Product Technology Development Laboratory, Tanabe Seiyaku Co., Ltd., 16-89, Kashima 3-chome, Osaka 532-8505, Yodogawa, Japan. nish-h@tanabe.co.jp
Journal of Biochemical and Biophysical Methods
|May 18, 2001
Abstract:
Various noncyclic mono-, oligo- and polysaccharides have been successfully used for enantiomer separation in the analytical sciences such as HPLC and capillary electrophoresis (CE). This review presents enantiomer separation by CE utilizing mainly polysaccharides as chiral additives. The operation conditions that affect the enantioselectivity are briefly discussed.