Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Phase plane analysis of left ventricular hemodynamics.

S A Eucker1, J B Lisauskas, J Singh

  • 1Cardiovascular Biophysics Laboratory, Washington University, St. Louis, Missouri 63110, USA.

Journal of Applied Physiology (Bethesda, Md. : 1985)
|May 18, 2001
PubMed
Summary

Phase plane analysis of left ventricular (LV) pressure contours offers new insights into cardiac function. This method quantifies novel attributes, enhancing the characterization of ventricular performance beyond standard hemodynamic indexes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Echocardiographic characterization of fundamental mechanisms of abnormal diastolic filling in diabetic rats with a parameterized diastolic filling formalism.

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography·2001
Same author

Chamber properties from transmitral flow: prediction of average and passive left ventricular diastolic stiffness.

Journal of applied physiology (Bethesda, Md. : 1985)·2001
Same author

Induction of spermatogenesis by androgens in gonadotropin-deficient (hpg) mice.

Endocrinology·1995
Same author

Dysfibrinogenemia: a case with thrombosis (fibrinogen Richfield) and an overview of the clinical and laboratory spectrum.

American journal of hematology·1995
Same author

Oxygen is cost effective.

Anesthesia and analgesia·1995
Same author

"Bleeding polyp" of the osseous nasal septum: a rarely seen lesion.

American journal of otolaryngology·1995

Area of Science:

  • Cardiovascular Physiology
  • Cardiac Mechanics
  • Biomedical Engineering

Background:

  • Standard hemodynamic indexes provide limited physiological information from left ventricular (LV) pressure contours.
  • Novel quantitative methods are needed to fully characterize ventricular function.

Purpose of the Study:

  • To extract additional physiological insights from time-dependent LV pressure data.
  • To explore the utility of phase plane analysis for characterizing ventricular function.

Main Methods:

  • Utilized phase plane analysis on high-fidelity LV pressure data from cardiac catheterization.
  • Derived standard hemodynamic indexes and novel attributes from the pressure loops.

Main Results:

Related Experiment Videos

  • Phase plane analysis readily provided standard LV systolic and diastolic function indexes.
  • Novel metrics including loop area, isovolumic relaxation time constant, and beat-to-beat coupling were characterized.
  • Quantified pressure asymmetry and load dependence during isovolumic phases.

    • Conclusions:

    • Phase plane analysis offers a novel approach for physiological discovery in cardiac function.
    • This method presents theoretical and applied advantages for quantitative ventricular characterization.