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Updated: Aug 3, 2026

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia
Published on: May 9, 2013
[Single-staged operation for the patients with concomitant diseases of coronary and carotid arteries]
K Matsuzaki1, Y Matsui, N Shiiya
1Department of Cardiovascular Surgery, Hokkaido University School of Medicine, Sapporo, Japan.
Insights
Combined surgical procedures for severe coronary and carotid artery stenosis effectively prevent perioperative complications. This approach is desirable for patients needing coronary artery bypass grafting (CABG) and cerebral revascularization.
Area of Science:
- Cardiovascular Surgery
- Neurological Surgery
- Vascular Surgery
Context:
- Concomitant severe stenosis in coronary and carotid arteries presents a complex surgical challenge.
- Patients requiring coronary artery bypass grafting (CABG) may also have significant extracranial carotid stenosis.
- Symptomatic carotid stenosis necessitates cerebral revascularization to prevent stroke.
Purpose:
- To evaluate the safety and efficacy of combined coronary artery bypass grafting (CABG) and cerebral revascularization procedures.
- To assess the feasibility of performing carotid endarterectomy (CEA) or carotid artery bypass grafting concurrently with CABG.
- To determine the potential for avoiding perioperative myocardial infarction and neurological complications.
Summary:
- Four cases of concomitant severe coronary and carotid stenosis treated with combined procedures are described.
- Cerebral revascularization included carotid endarterectomy (CEA) in three patients and carotid artery bypass grafting in one.
- One patient underwent percutaneous transluminal stenting of the internal carotid artery before combined left CEA and CABG.
- No perioperative myocardial infarction or neurological complications were observed in any of the cases.
Impact:
- Combined procedures for severe coronary and carotid stenosis are safe and effective.
- This combined approach can successfully prevent major perioperative complications like myocardial infarction and stroke.
- The study highlights the desirability of combined cerebral revascularization and CABG in select patient populations.
Abstract:
The authors describe four cases with concomitant coronary and carotid severe stenosis operated by combined procedure. As the cerebral revascularization, carotid endarterectomy (CEA) was performed for three patients, while carotid artery bypass grafting was performed for the other one. In one patient with bilateral carotid stenosis, percutaneous transluminal stenting of the right internal carotid artery was performed one day before combined left CEA and coronary artery bypass grafting (CABG). Both perioperative myocardial infarction and neurological complication could be avoided in each case. When a CABG candidate also has significant extracranial carotid stenosis with clinical symptoms, combined cerebral revascularization and CABG is desirable.
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