Benign tumefactive soft tissue extension from Paget's disease of bone simulating malignancy

Area of Science:

• Oncology
• Orthopedic Surgery
• Radiology

Background:

• Paget's disease of bone is a chronic condition characterized by abnormal bone remodeling.
• Osteosarcoma is a primary bone malignancy that can arise as a complication of Paget's disease.
• Radiographic assessment is crucial for differentiating benign from malignant bone lesions.

Observation:

• A case of Paget's disease of bone presented with a clinically concerning extraosseous mass.
• The imaging findings initially suggested a malignant tumor with soft tissue extension.
• Histopathological examination confirmed a benign nature of the observed mass.

Findings:

• The reported case demonstrates a benign manifestation of Paget's disease that radiographically simulates osteosarcoma.
• The presence of an extraosseous mass, typically associated with malignancy, was observed in a benign context.
• This highlights the importance of considering benign mimics in the differential diagnosis.

Implications:

• Accurate diagnosis is essential to avoid unnecessary aggressive treatment for benign conditions.
• Radiologists and clinicians should be aware of rare benign presentations of Paget's disease.
• This case contributes to the understanding of the diverse clinical and radiographic spectrum of Paget's disease complications.