Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Measuring extraocular muscle volume using dynamic contours.

M J Firbank1, R M Harrison, E D Williams

  • 1University Department of Radiology, Royal Victoria Infirmary, Newcastle Upon Tyne NE1 4LP, England, UK. m.j.firbank@ncl.ac.uk

Magnetic Resonance Imaging
|May 19, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Changes in DTI-ALPS index and its associations with neuronal damage in Lewy body disease.

Parkinsonism & related disorders·2025
Same author

Uptake and experience of professional interpreting services in primary care in a South Asian population: a national cross-sectional study.

BMC primary care·2024
Same author

Automating Quantitative Measures of an Established Conventional MRI Scoring System for Preterm-Born Infants Scanned between 29 and 47 Weeks' Postmenstrual Age.

AJNR. American journal of neuroradiology·2021
Same author

Cancer-associated fibroblasts of the prostate promote a compliant and more invasive phenotype in benign prostate epithelial cells.

Materials today. Bio·2020
Same author

Vedolizumab as a rescue therapy for patients with medically refractory Crohn's disease.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2018
Same author

p49/STRAP, a Serum Response Factor Binding Protein (SRFBP1), Is Involved in the Redistribution of Cytoskeletal F-Actin Proteins during Glucose Deprivation.

The journal of nutrition, health & aging·2017
Same journal

Systematic comparison of MPRAGE and BRAVO T1-weighted MRI pulse sequences and brain morphometry in high-risk young adults.

Magnetic resonance imaging·2026
Same journal

Foot dynamic contrast-enhanced MRI for assessing microcirculatory changes after endovascular therapy in peripheral artery disease: A prospective pilot study.

Magnetic resonance imaging·2026
Same journal

Reconstruction of MRI from undersampled k-spaces of double-contrast volume acquisitions using deep neural networks.

Magnetic resonance imaging·2026
Same journal

Radiofrequency-induced heating safety of brain MRI scans at 7 T in the presence of a shoulder implant.

Magnetic resonance imaging·2026
Same journal

Incremental diagnostic value of microstructural time-dependent diffusion MRI in differentiating PCNSL from glioblastoma over conventional MRI.

Magnetic resonance imaging·2026
Same journal

Enhanced respiratory motion compensation in free-breathing dynamic contrast-enhanced MRI with GROG-facilitated bunch phase encoding and Golden angle radial sampling.

Magnetic resonance imaging·2026
See all related articles

An automated MRI technique accurately measures extraocular muscle volume in thyroid-associated ophthalmopathy (TAO). This rapid, reproducible method aids in monitoring treatment effects on eye muscle enlargement.

Area of Science:

  • Ophthalmology
  • Radiology
  • Medical Imaging

Background:

  • Thyroid-associated ophthalmopathy (TAO) involves extraocular muscle enlargement.
  • Monitoring treatment effects requires accurate measurement of muscle volume.
  • Orbital MRI is a key imaging modality for TAO assessment.

Purpose of the Study:

  • To develop and validate an automated technique for estimating extraocular muscle volumes from 3D orbital MRI datasets.
  • To assess the accuracy, reproducibility, and speed of the automated method compared to manual outlining.

Main Methods:

  • Development of an automated segmentation technique for 3D orbital MRI data.
  • Minimal operator input required for the automated process.
  • Verification using simulated datasets and real patient data, comparing automated results with manual measurements.

Related Experiment Videos

Main Results:

  • The automated technique demonstrated high accuracy, with volumes 1.6% less than manual outlining on patient data (SD 13%).
  • Repeatability was excellent, with a coefficient of variation of 1.0% for the automated method versus 4% for manual outlining.
  • The automated method significantly reduced processing time from 20 minutes (manual) to 7 minutes (automated).

Conclusions:

  • The automated technique provides a rapid, reproducible, and accurate method for quantifying extraocular muscle volumes in TAO.
  • This automated approach can improve the monitoring of medical treatment efficacy in TAO patients.
  • The technique minimizes errors associated with manual segmentation and repositioning in serial MRI examinations.