[Effect of acute irradiation on the exocrine secretion of pancreas in pig]

Six fistulated pigs have been used in this experiment to study the effect, on the exocrine pancreatic secretion, of a partial acute irradiation, at 600 rd and 800 rd. Whatever the dose, the irradiation provoked an immediate and temporary decrease of the pancreatic secretion. The normal values were reached after the 8th day post-irradiation. Furthermore, a direct effect on the synthesis of amylase and lipase was shown. The synthesis of trypsin and chymotrypsin was not modified by irradiation.