Related Experiment Video
Updated: Aug 9, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Congenital heart disease and cardiac surgery in childhood: effects on cognitive function and academic ability
1Paediatric Surgical Unit, Harefield Hospital, Harefield, Middlesex UB9 6JH, UK. j.wray@rbh.nthames.nhs.uk
Insights
Cardiac surgery in children with congenital heart disease did not improve cognitive function. Cyanotic heart lesions, unlike acyanotic ones, were linked to persistent deficits in cognitive and academic performance post-surgery.
Area of Science:
- Pediatric Cardiology
- Neurodevelopmental Pediatrics
- Congenital Heart Disease
Background:
- Congenital heart disease (CHD) affects children's development.
- Cognitive and academic functioning in children with CHD is a concern.
- The impact of cardiac surgery on neurodevelopment requires further investigation.
Purpose of the Study:
- To assess cognitive and academic changes after cardiac surgery in children with CHD.
- To compare outcomes between children with cyanotic and acyanotic lesions.
- To evaluate the long-term effects of cardiac surgery on neurodevelopment.
Main Methods:
- Prospective cross-sectional study with assessments before and 12 months after treatment.
- Included children aged 3.5-17 years with CHD, those awaiting bone marrow transplantation, and a healthy control group.
- Cognitive and academic functioning measured using Intelligence Quotient and British Ability Scales.
Main Results:
- Preoperatively, children with cyanotic lesions had cognitive deficits compared to those with acyanotic lesions.
- Postoperatively, cyanotic CHD patients showed performance deterioration and lower academic scores.
- Differences between CHD and bone marrow transplantation groups diminished by follow-up.
Conclusions:
- Cardiac surgery does not appear to improve early postoperative cognitive function in children with CHD.
- The type of cardiac lesion (cyanotic vs. acyanotic) remains a significant factor influencing cognitive and academic outcomes.
- Findings contrast with previous studies suggesting potential postoperative benefits.
Objective:
To evaluate changes in cognitive and academic functioning following cardiac surgery in children with congenital heart disease.
Design:
A prospective cross sectional study in which patients were assessed immediately before treatment and 12 months later.
Patients:
Three groups of children aged 3.5-17 years: a group with congenital heart disease awaiting surgery, another awaiting bone marrow transplantation, and a healthy comparison group.
Main Outcome Measures:
Intelligence quotient and measures of academic attainment, evaluated with the British Ability Scales.
Results:
Preoperatively, children with cyanotic lesions showed deficits in comparison with those with acyanotic lesions. Postoperatively, children with cyanotic lesions showed a deterioration in performance and achieved significantly lower scores than those with acyanotic lesions. While there were significant differences between the congenital heart disease and bone marrow transplantation groups preoperatively, these were no longer apparent at follow up.
Conclusions:
In contrast to previously published findings, the present results suggest that cardiac surgery does not result in early postoperative improvements in cognitive function for children with congenital heart disease. The nature of the cardiac lesion continues to affect cognitive and academic performance, even after surgery.
Related Concept Videos
Rheumatic Heart Disease I: Introduction
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Language and Cognition
Information Processing Approach
Attention-Deficit/Hyperactivity Disorder
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Learning Disabilities
Dyslexia
Dyslexia is a...

