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Related Experiment Videos

Diabetic autonomic neuropathy.

A M Ahmed1, A Hussein, N H Ahmed

  • 1Department of Medicine, University of Bahr Elghazal, PO Box 102, Khartoum, Sudan. Awad_sd@hotmail.com

Saudi Medical Journal
|May 22, 2001
PubMed
Summary
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Diabetic autonomic neuropathy is common in Sudanese patients, affecting 40%. This condition is linked to longer diabetes duration, poor glycemic control, and peripheral neuropathy.

Area of Science:

  • Endocrinology
  • Neurology
  • Diabetology

Background:

  • Diabetic autonomic neuropathy (DAN) is under-researched in medical literature.
  • Understanding DAN's prevalence and risk factors in diverse populations is crucial for effective management.

Purpose of the Study:

  • To investigate the prevalence of DAN in Sudanese diabetic patients.
  • To explore the association between DAN and glycemic control, diabetes duration, and peripheral neuropathy.

Main Methods:

  • A cohort of 120 diabetic patients and 42 age-matched controls underwent cardiovascular autonomic function tests.
  • Clinical history, physical examination, glycemic control (HbA1c), and peripheral neuropathy assessments were performed.

Main Results:

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  • DAN was diagnosed in 40% of diabetic patients (48/120).
  • Significant associations were found between DAN and longer diabetes duration (P<0.001), poor glycemic control (0.01>P>0.001), and peripheral neuropathy (0.02>P>0.01).

Conclusions:

  • Diabetic autonomic neuropathy is a prevalent condition in Sudanese diabetic patients, encompassing both symptomatic and asymptomatic cases.
  • Prolonged diabetes duration, inadequate glycemic control, and co-existing peripheral neuropathy are significant risk factors for DAN.
  • Increased awareness among healthcare providers regarding DAN's presentation and diagnostic methods is essential.