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New onset diabetes mellitus in an HIV-positive adolescent
I Abdel-Khalek1, H J Moallem, S Fikrig
1Department of Pediatrics, SUNY Health Science Center at Brooklyn, USA.
AIDS Patient Care and Stds
|May 22, 2001
Abstract:
The authors report an 18-year-old girl with HIV infection who developed new-onset insulin-dependent diabetes mellitus (IDDM) in association with anemia. IDDM among patients with HIV infection has been infrequently reported and suggested to be caused by different etiologies. Susceptibility to autoimmune diseases, such as IDDM, has been associated functionally with two members of a newly described multigene family called PERB11. In this patient, the progression of hyperglycemia associated with a rapid increase in insulin requirement is suggestive of insulin resistance.