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Multi-slice CT for visualization of pulmonary embolism using perfusion weighted color maps
J E Wildberger1, M U Niethammer, E Klotz
1Department of Diagnostic Radiology, University of Technology, Aachen, Germany. wildberg@rad.rwth-aachen.de
Rofo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin
|May 23, 2001
Summary
This study introduces a new multi-slice CT technique for visualizing pulmonary embolism (PE). The method displays lung parenchymal density, showing decreased areas in patients with PE, aiding diagnosis.
Area of Science:
- Radiology
- Medical Imaging
- Pulmonary Medicine
Background:
- Pulmonary embolism (PE) diagnosis relies on imaging techniques.
- Multi-slice CT (MSCT) is a standard tool for evaluating PE.
- Accurate visualization of lung parenchyma density is crucial for PE detection.
Purpose of the Study:
- To assess the feasibility of a novel perfusion-weighted color display technique.
- To visualize lung parenchyma density derived from MSCT data for PE detection.
- To evaluate a new functional imaging methodology for suspected PE.
Main Methods:
- Utilized MSCT with intravenous contrast medium administration.
- Developed a new image processing technique for automated 3D lung segmentation.
- Color-encoded display of parenchymal density overlaid on original CT images.
Main Results:
- Homogeneous density distribution observed in patients without PE.
- Decreased density values detected distally to occluded pulmonary arteries in PE patients.
- Perfusion-weighted color maps revealed abnormalities in PE cases.
Conclusions:
- Lung densitometry with optimized display offers potential additional information for PE diagnosis.
- The technique shows promise for functional imaging in suspected or proven PE.
- Further studies with larger patient cohorts and comparison to V/Q scintigraphy are warranted.