Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Percutaneous ethanol injection: single session treatment.

F Meloni1, S Lazzaroni, T Livraghi

  • 1Department of Radiology, Ospedale Civile di Vimercate, Via Cesare Battisti 23, I-20059 Vimercate, Milan, Italy. lalivra@tin.it

European Journal of Ultrasound : Official Journal of the European Federation of Societies for Ultrasound in Medicine and Biology
|May 23, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evidence for the Collective Nature of Radial Flow in Pb+Pb Collisions with the ATLAS Detector.

Physical review letters·2026
Same author

Evidence for the Dimuon Decay of the Higgs Boson in pp Collisions with the ATLAS Detector.

Physical review letters·2025
Same author

Evidence for Longitudinally Polarized W Bosons in the Electroweak Production of Same-Sign W Boson Pairs in Association with Two Jets in pp Collisions at sqrt[s]=13  TeV with the ATLAS Detector.

Physical review letters·2025
Same author

Observation of tt[over ¯] Production in Pb+Pb Collisions at sqrt[s_{NN}]=5.02  TeV with the ATLAS Detector.

Physical review letters·2025
Same author

Search for Dark Matter Produced in Association with a Dark Higgs Boson in the bb[over ¯] Final State Using pp Collisions at sqrt[s]=13  TeV with the ATLAS Detector.

Physical review letters·2025
Same author

A novel missense variant of <i>FBN1</i> gene in a Sardinian family with Marfan syndrome: a case report.

Frontiers in pediatrics·2025

Single session percutaneous ethanol injection (PEI) effectively treats hepatocellular carcinoma (HCC), especially larger or multiple tumors. While comparable to traditional PEI for necrosis, it offers faster treatment and broader applicability.

Area of Science:

  • Hepatobiliary oncology
  • Interventional radiology
  • Minimally invasive cancer therapy

Background:

  • Percutaneous ethanol injection (PEI) is a standard treatment for hepatocellular carcinoma (HCC) in cirrhotic patients.
  • Traditional PEI offers good efficacy, safety, and cost-effectiveness compared to surgical resection.
  • A 'single session' PEI technique was developed for larger HCC under general anesthesia.

Purpose of the Study:

  • To evaluate the efficacy and outcomes of single session PEI for treating large or multiple HCC.
  • To compare the effectiveness of single session PEI in different HCC types (encapsulated, infiltrating, advanced).

Main Methods:

  • A study involving 108 patients with HCC greater than 5 cm in diameter.
  • Patients were divided into three groups: Group A (single, encapsulated lesions 5-8.5 cm), Group B (single, infiltrating lesions 5-10 cm or multiple HCC), and Group C (advanced disease).

Related Experiment Videos

  • Treatment involved single session PEI under general anesthesia.

    • Main Results:

    • Complete necrosis was achieved in 58.3% of encapsulated lesions (Group A).
    • Complete necrosis was only achieved in encapsulated lesions in Group B; it was not obtained in infiltrating lesions of Groups B and C.
    • Three-year survival rates were 57% for encapsulated HCC, 42% for infiltrating/multiple HCC, and 0% for advanced HCC. Major complications included hemorrhage and hepatic decompensation.

    Conclusions:

    • Single session PEI demonstrates comparable efficacy to traditional PEI in inducing liver tumor necrosis.
    • This technique is advantageous for treating larger and multiple HCC lesions with reduced treatment time.
    • Single session PEI represents a more aggressive therapeutic approach than traditional PEI.