Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Alveolar type II cell apoptosis.

L M Sutherland1, Y S Edwards, A W Murray

  • 1School of Biological Sciences, Faculty of Science and Engineering, Flinders University of South Australia, GPO Box 2100, 5001, South Australia, Adelaide, Australia. leanne.sutherland@flinders.edu.au

Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
|May 23, 2001
PubMed
Summary

Alveolar type II cell apoptosis is crucial for lung health and disease. Understanding its signaling pathways may lead to new treatments for acute lung injury and other pulmonary disorders.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Maximising the impact of your work using infographics.

Bone & joint research·2017
Same author

Quantification of radiation exposure in the operating theatre during management of common fractures of the upper extremity in children.

Annals of the Royal College of Surgeons of England·2016
Same author

Slipped capital femoral epiphysis: is it worth the risk and cost not to offer prophylactic fixation of the contralateral hip?

The bone & joint journal·2015
Same author

Synthetic versus plaster of Paris casts in the treatment of fractures of the forearm in children: a randomised trial of clinical outcomes and patient satisfaction.

The bone & joint journal·2013
Same author

The effect of posterior spinal fusion on respiratory function in Duchenne muscular dystrophy.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2012
Same author

Seasonal variation in the effects of hard substratum biofilming on settlement of marine invertebrate larvae.

Biofouling·2011

Area of Science:

  • Pulmonary Medicine
  • Cell Biology
  • Apoptosis Research

Background:

  • Alveolar type II cells are vital for lung function, producing surfactant and acting as progenitor cells.
  • Apoptosis, or programmed cell death, plays a key role in maintaining alveolar epithelium homeostasis.
  • Evidence suggests apoptosis in alveolar type II cells is involved in normal lung development and disease.

Purpose of the Study:

  • To review apoptotic signaling pathways in alveolar type II cells.
  • To describe the functions of alveolar type II cell apoptosis in healthy and diseased lungs.

Main Methods:

  • Literature review of studies on alveolar type II cell apoptosis.
  • Analysis of signaling pathways involved in apoptosis.
  • Discussion of physiological and pathological roles.

Related Experiment Videos

Main Results:

  • Alveolar type II cells undergo apoptosis during lung development and injury.
  • Apoptosis is essential for normal lung maturation and repair processes.
  • Dysregulation of apoptosis contributes to lung pathologies.

Conclusions:

  • Understanding alveolar type II cell apoptosis is critical for lung health.
  • Targeting apoptotic pathways may offer therapeutic strategies for lung diseases.
  • Further research into signaling transduction pathways is warranted for novel treatments.