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Symptomatic rickets in adolescence.

H Narchi1, M El Jamil, N Kulaylat

  • 1Al-Hasa Specialty Services Division, Saudi Aramco-Al-Hasa Health Center, Box 6030, Mubarraz 31311, Saudi Arabia. hassibnarchi@hotmail.com

Archives of Disease in Childhood
|May 23, 2001
PubMed
Summary
This summary is machine-generated.

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Adolescents, particularly females, are at risk of rickets even in sunny regions. Common symptoms include hypocalcemic tetany and limb pain, highlighting the need for awareness despite potential lack of radiological evidence.

Area of Science:

  • Pediatrics
  • Endocrinology
  • Nutritional Science

Background:

  • Rickets, a condition causing bone softening, can affect adolescents.
  • Risk factors include inadequate nutrition and limited sun exposure.
  • Symptomatic rickets in adolescents requires detailed clinical and biochemical assessment.

Purpose of the Study:

  • To describe the clinical characteristics of symptomatic rickets in adolescents.
  • To investigate the prevalence, presentation, and contributing factors of rickets in this age group.

Main Methods:

  • Retrospective case series of 21 adolescents (aged 10-15 years) diagnosed with symptomatic rickets.
  • Assessment included clinical presentation, biochemical tests (calcium, phosphate, vitamin D, alkaline phosphatase, parathormone), radiological evaluation, dietary intake, and sun exposure.

Related Experiment Videos

  • Data collected from a hospital in Saudi Arabia between January 1996 and December 1997.

    • Main Results:

    • Prevalence of symptomatic rickets was 68 per 100,000 child-years, predominantly in females (20/21).
    • Common presentations were carpopedal spasms (n=12), limb pains (n=6), and lower limb deformities (n=2).
    • Biochemical findings frequently included hypocalcemia (n=19) and low 25-hydroxyvitamin D (n=7); radiological evidence was not universal (n=8).

    Conclusions:

    • Adolescents, especially females, face rickets risk even in sunny climates.
    • Inadequate dietary calcium and vitamin D intake, coupled with limited sun exposure, were significant contributing factors.
    • Hypocalcemic tetany and limb pain are key indicators, emphasizing clinical suspicion over sole reliance on radiological findings.