Rectal pulse granuloma

T C Pereira1, J W Prichard, M Khalid

  • 1Department of Pathology and Laboratory Medicine, Allegheny General Hospital, Pittsburgh, PA 15212, USA.

Insights

This study reports the first case of pulse granuloma in the rectum, a rare benign condition often caused by vegetable matter. Recognizing its unique features is key to accurate diagnosis and avoiding misidentification with other rectal lesions.

Area of Science:

  • Gastroenterology
  • Pathology

Background:

  • Pulse granuloma is a rare benign condition.
  • It is typically a foreign body reaction to vegetable particles, commonly found in the oral cavity or lungs.

Observation:

  • A case of pulse granuloma involving the rectum is presented.
  • The patient exhibited a submucosal and intramuscular mass lesion during routine rectal examination and colonoscopy.

Findings:

  • Microscopic examination of the excised mass revealed characteristic features of pulse granuloma.
  • These included acute and chronic inflammatory cells, foreign-body giant cells, vegetable matter, and distinctive hyaline rings and granular structures.

Implications:

  • This is the first reported case of rectal pulse granuloma.
  • Familiarity with its histopathologic features can prevent diagnostic delays and unnecessary investigations for similar-looking rectal conditions.

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