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Related Experiment Videos

Spontaneous surface wrinkling retinopathy.

M J Scudder, D E Eifrig

    Annals of Ophthalmology
    |March 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Spontaneously occurring surface wrinkling retinopathy is usually benign, but can cause significant vision loss in some cases. This condition involves retinal wrinkling, tortuous vessels, and hemorrhages, potentially linked to ischemia and vitreous changes.

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    Area of Science:

    • Ophthalmology
    • Retinal Diseases
    • Vascular Biology

    Background:

    • Spontaneously occurring surface wrinkling retinopathy (SRR) is a rare condition.
    • SRR is not associated with prior surgery, retinal vascular disease, or ocular inflammation.

    Purpose of the Study:

    • To describe the clinical features, course, and potential causes of spontaneously occurring surface wrinkling retinopathy.
    • To emphasize the role of fluorescein leakage in the pathogenesis of SRR.

    Main Methods:

    • Retrospective case series of 17 eyes from 16 patients with SRR.
    • Ophthalmoscopic examination and fluorescein angiography were utilized.
    • Patient history and follow-up data were reviewed.

    Main Results:

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    • SRR presented with a wrinkled shagreen appearance, tortuous vessels, and intraretinal hemorrhages.
    • Fluorescein leakage into the retina was a prominent finding.
    • While often benign, 2 eyes experienced significant visual deterioration to 20/300.

    Conclusions:

    • Spontaneously occurring surface wrinkling retinopathy is typically benign but carries a risk of visual impairment.
    • Mild chronic ischemia and posterior vitreous collapse are proposed as potential causative mechanisms.
    • Further research into the pathogenesis and management of SRR is warranted.