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Blood lead in children and its determinants in Nagpur, India
A B Patel1, S V Williams, H Frumkin
1Clinical Epidemiology Unit, Indira Gandhi Medical College, Nagpur, India.
Insights
High blood lead levels are prevalent in Indian children, with significant risk factors including lead-based paint and eye cosmetics. Environmental sources like paint and clay show high lead content, indicating a major public health issue.
Area of Science:
- Environmental Health
- Pediatric Toxicology
- Public Health
Background:
- Elevated blood lead (PbB) levels pose a significant risk to children's health.
- Understanding local risk factors is crucial for targeted interventions, especially in diverse settings like India.
Purpose of the Study:
- To determine the prevalence of elevated PbB levels in children aged 6 months to 6 years in an Indian city.
- To identify associated risk factors and analyze lead content in environmental sources.
Main Methods:
- A community-based cross-sectional study involving 297 children.
- Assessment of blood lead levels (PbB) and potential environmental lead sources.
- Statistical analysis to identify risk factors for elevated PbB.
Main Results:
- A high prevalence of elevated PbB (67%) was observed, with a mean of 18.4 microg/dL.
- Key risk factors included living in houses with lead-based paint (OR 6.42), recent exposure to lead-based paint (OR 2.61), and use of the eye cosmetic 'ma' (OR 2.63).
- High lead levels were found in environmental sources like paint, pencils, crayons, and clay.
Conclusions:
- Environmental lead exposure is a significant health problem for children in this Indian city.
- Risk factors identified differ from those commonly reported in other countries, highlighting the need for context-specific strategies.
- Interventions should focus on reducing exposure to lead-based paints and traditional eye cosmetics.
Abstract:
In a community-based cross-sectional study of 297 children aged 6 months to 6 years in an Indian city, the authors assessed the prevalence of elevated (> or = 10 microg/dL) blood lead (PbB) levels, their risk factors, and the lead contents in potential environmental sources. Mean PbB was 18.4 microg/dL +/- 16.5. The prevalence of elevated PbB was 67%. Anticipated risk factors for elevated PbB were living in houses painted with lead-based paint, odds ratio (OR) 6.42 (1.75, 23.6; p = 0.005), recent exposures to lead-based paint, OR 2.61 (1.07, 6.66; p = 0.03), and the use of the eye cosmetic ma," OR 2.63 (1.24, 5.56; p = 0.01). Unanticipated results were effect of upper caste as a risk factor, OR (adjusted) 1.85 (95% CI = 0.96, 3.57; p = 0.06), and the lack of effect of traffic, parental occupational exposure, or nutritional status. Analysis of various environmental sources such as paint, pencils, crayons, and clay revealed high lead levels. These results demonstrate the existence of a major environmental health problem in Indian children, with risk factors that differ from those in other countries.
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