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Published on: November 3, 2016
Pediatric neurologic emergencies
P G Meyer1, S Ducrocq, P Carli
1Pediatric Neurointensive Care Unit, Department of Anesthesiology and Critical Care Medicine, Centre Hospitalier Universitaire Necker Enfants Malades et Université V, Paris, France. philippe.meyer@nck.ap-hop-paris
Insights
Critical care for neuroemergencies focuses on stabilizing patients and preventing secondary brain damage. Prompt, multimodal management improves outcomes in severe pediatric brain injuries and other critical neurological conditions.
Area of Science:
- Pediatric Critical Care Medicine
- Pediatric Neurology
- Neurocritical Care
Background:
- Neuroemergencies involve life-threatening conditions causing secondary brain lesions.
- Prompt critical care is essential to halt self-aggravating pathological processes.
Purpose of the Study:
- To outline the critical care management of neuroemergencies in children.
- To emphasize multimodal monitoring and tailored interventions for improved outcomes.
Main Methods:
- Initial resuscitation includes airway control, hemodynamic, and hydroelectrolytic stabilization.
- Computed tomography guides surgical decompression for mass lesions.
- Multimodal monitoring includes normoventilation, sedation, osmotherapy, and mean arterial pressure optimization.
Main Results:
- Optimizing cerebral blood flow and metabolism, beyond solely controlling cerebral perfusion pressure, is crucial.
- Transcranial Doppler and jugular bulb oxygen saturation monitoring aid in assessing cerebral blood flow and metabolism.
Conclusions:
- Efficient emergency management of neuroemergencies can improve outcomes.
- Conditions like severe brain injuries, arteriovenous malformation rupture, status epilepticus, and acute hydrocephalus benefit from timely critical care.
Abstract:
Neuroemergencies are life-threatening situations in which, whatever the cause, common pathologic phenomena result in secondary brain lesions. The goal of critical care management is to stop these self-aggravating processes as soon as possible. Initial resuscitation is devoted to control of the airway and hemodynamic and hydroelectrolytic stabilization. With mass lesions, minimal computed tomographic exploration immediately precedes surgical decompression. Further critical care adapted to the child's needs requires multimodal monitoring. Normoventilation, deep sedation, osmotherapy with mannitol or hypertonic saline solutions, and optimization of mean arterial pressure are the basis of management. A purely pressure-driven approach aimed at controlling cerebral perfusion pressure could be potentially harmful, and associated measurement of blood flow velocity with transcranial Doppler and jugular bulb oxygen saturation monitoring allows an approach to cerebral blood flow and metabolism. Outcome can be improved in dangerous situations such as severe brain injuries, cerebral arteriovenous malformation rupture, status epilepticus, and acute hydrocephalus, provided that emergency management could be applied efficiently.
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