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Generation and Grafting of Tissue-engineered Vessels in a Mouse Model
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Vascular repair processes mediated by transforming growth factor-beta

V Lindner1

  • 1Center for Molecular Medicine, Maine Medical Center Research Institute, 81 Research Drive, Scarborough, ME 04074. lindnv@mmc.org

Zeitschrift Fur Kardiologie
|May 26, 2001
PubMed
Summary

Transforming growth factor-beta (TGF-beta) signaling mediates arterial repair after injury. Inhibiting this pathway with TGF-beta R:Fc reduces intimal hyperplasia and negative remodeling, crucial for preventing restenosis.

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