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Micromotions of bladder wall in chronic pelvic pain (CPP): a pilot study
P Van Os-Bossagh1, L M Kosterman, W C Hop
1Department of Obstetrics and Gynaecology, University Hospital Dijkzigt, Rotterdam, The Netherlands.
Summary
This study found significant differences in bladder wall micromotions (MM) in women with chronic pelvic pain (CPP). These findings suggest the bladder plays a role in CPP, offering new insights for chronic pelvic pain research.
Area of Science:
- Urology
- Gynecology
- Physiology
Background:
- Chronic pelvic pain (CPP) is a complex condition with multifactorial origins.
- The role of the bladder wall in the pathophysiology of CPP remains incompletely understood.
Purpose of the Study:
- To investigate the occurrence and duration of bladder wall micromotions (MM) in women with CPP compared to healthy controls.
- To explore potential associations between bladder activity and chronic pelvic pain.
Main Methods:
- Micromotion detection (MMD) using a catheterized latex balloon with eight electrodes placed in the bladder.
- Simultaneous registration of bladder wall micromotions, intravesical pressure, abdominal pressure, and respiratory excursions.
- Comparison of MM activity and detrusor pressure variations between 30 women with CPP and 7 healthy controls.
Main Results:
- A statistically significant difference in both the duration and frequency of occurrence of MM activity was observed between women with CPP and the control group.
- A trend towards significance was noted for variations in detrusor pressure between the two groups.
Conclusions:
- The study provides evidence indicating the bladder wall is involved in the manifestation of chronic pelvic pain.
- These findings suggest that bladder micromotions may be a relevant factor in CPP and warrant further investigation.