Tunneled epidural catheters for prolonged analgesia in pediatric patients

L Aram1, E J Krane, L J Kozloski

  • 1Department of Anesthesia, Stanford University, Stanford, California 94305-5640, USA.

Insights

Subcutaneously tunneled epidural catheters offer safe and effective prolonged pain management in pediatric patients unresponsive to conventional opioid therapy. This technique provides significant analgesia, reduces opioid use, and has a low complication rate.

Area of Science:

  • Pediatric Pain Management
  • Anesthesiology
  • Palliative Care

Background:

  • Prolonged pain in children often requires advanced management strategies.
  • Conventional opioid therapy may be insufficient or impractical for certain pediatric pain conditions.
  • Subcutaneously tunneled epidural catheters offer an alternative for extended analgesia.

Observation:

  • A retrospective study reviewed 25 pediatric patients with prolonged pain unresponsive to conventional therapy.
  • Patients received thoracic, lumbar, or caudal tunneled epidural catheters for pain management.
  • Indications included end-stage malignancy, extensive abdominal surgery, and trauma.

Findings:

  • Tunneled epidural catheters were effective in providing extended analgesia for all pediatric subjects.
  • Opioid requirements were significantly reduced or eliminated in patients with chronic pain.
  • The technique demonstrated a low incidence of serious local or systemic complications.

Implications:

  • Subcutaneously tunneled epidural catheters are a safe and effective option for managing prolonged pediatric pain.
  • This method can reduce the need for systemic opioids and improve patient outcomes.
  • The technique is valuable for children experiencing pain refractory to conventional treatments.
Abstract

Related Concept Videos

Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
Analgesia and Pain Management01:25

Analgesia and Pain Management

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
Parenteral Anesthetics: Overview01:24

Parenteral Anesthetics: Overview

Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
Parentral Nutrition: Centeral and Peripheral Parental Nutrition01:27

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...