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ACP Best Practice No 164: Necropsy techniques in ophthalmic pathology
1Ophthalmic Sciences Unit, Royal Hallamshire Hospital (Floor O), Glossop Road, Sheffield S10 2JF, UK. a.parsons@sheffield.ac.uk
Journal of Clinical Pathology
|May 29, 2001
Summary
Pathological examination of the eye and adnexal structures at necropsy provides crucial information for determining cause of death and understanding ocular diseases. This review details technical removal methods and emphasizes legal and ethical considerations for ocular tissue examination.
Area of Science:
- Ophthalmic Pathology
- Forensic Medicine
- Medical Ethics
Background:
- Necropsy examination of ocular and orbital tissues offers vital diagnostic information in both pediatric and adult cases.
- Findings can elucidate cause of death, particularly in cases of trauma (e.g., physical child abuse), and identify orbital diseases.
Purpose of the Study:
- To review technical methodologies for the removal of ocular and orbital tissues during necropsy.
- To discuss the critical legal and ethical considerations surrounding the post-mortem examination of ocular structures.
Main Methods:
- Detailed description of surgical techniques for excising the vitreous, globe (anterior approach), globe and orbital contents (posterior approach), globe, orbit, and orbital walls, and surrounding structures.
- Emphasis on culturally sensitive approaches, informed consent, and established protocols for tissue handling.
Main Results:
- The study outlines specific technical procedures for various levels of ocular and orbital tissue removal.
- It highlights the necessity of adhering to legal and ethical guidelines, including consent and tissue disposition.
Conclusions:
- Comprehensive pathological examination of the eye and adnexa is essential for forensic and clinical pathology.
- Best practices require a combination of precise technical skills and rigorous ethical and legal compliance.