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Management of medically refractory ascites
1Division of Surgical Oncology, Ohio State University, N924 Doan Hall, 410 W. 10th Avenue, Columbus, OH 43210, USA. zervos.2@OSU.edu
American Journal of Surgery
|May 30, 2001
Summary
Medically refractory ascites has limited treatment options. This review details current therapies for intractable ascites, aiding clinical decision-making for better patient palliation.
Area of Science:
- Hepatology
- Gastroenterology
- Internal Medicine
Background:
- Medically refractory ascites presents a significant clinical challenge with few effective therapeutic interventions.
- Current management strategies include diuresis, sodium restriction, shunts, liver transplantation, and large-volume paracentesis.
Purpose of the Study:
- To review and analyze existing therapeutic options for medically refractory ascites.
- To focus on the indications, benefits, and drawbacks of each treatment modality.
Main Methods:
- Literature review of past and current studies on intractable ascites.
- Incorporation of authors' clinical experience with cirrhotic and cancer patients.
Main Results:
- No single therapy is universally effective for refractory ascites.
- A range of treatments exist, each with specific applications and limitations.
Conclusions:
- Refractory ascites management is complex, often requiring a tailored approach.
- Thoughtful application of available therapies can improve palliation for patients who do not respond to initial medical management.