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This case report details a patient with eosinophilia and cardiac failure. Necropsy revealed left ventricular thrombus, myocardial fibrosis, and enlarged mesenteric lymph nodes, a novel finding in Löffler's endocarditis.
Area of Science:
- Cardiology
- Pathology
- Hematology
Background:
- Löffler's endocarditis is a rare cardiac condition.
- It is characterized by eosinophilia and cardiac involvement.
- Clinical and pathological findings are often severe.
Purpose of the Study:
- To report the clinical, laboratory, and necropsy findings in a patient with massive eosinophilia and fatal cardiac failure.
- To describe an additional pathological finding not previously reported in Löffler's endocarditis.
Main Methods:
- Clinical case presentation.
- Laboratory investigations.
- Necropsy examination.
Main Results:
- The patient presented with massive eosinophilia and fatal cardiac failure.
- Necropsy revealed partial obliteration of the left ventricle lumen by thrombus.
- Fibrous infiltration of the myocardium and massive enlargement of mesenteric lymph nodes were observed.
Conclusions:
- The findings expand the pathological spectrum of Löffler's endocarditis.
- Massive mesenteric lymph node enlargement may be associated with this condition.
- Further research is needed to understand the implications of these findings.
Abstract:
The clinical, laboratory, and necropsy findings in a patient with massive eosinophilia and fatal cardiac failure are reported. Necropsy revealed partial obliteration of the lumen of the left ventricle with dense white thrombus, and fibrous infiltration of the myocardium. An additional finding, not hitherto described in Löffler's endocarditis, was massive enlargement of the mesenteric lymph nodes.