Epileptic seizures and structural abnormalities in a patient with holoprosencephaly
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Updated: Oct 7, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
S Takahashi1, Y Takahashi, N Kondo
1Department of Pediatrics, Gifu University School of Medicine, 500-8705, Gifu, Japan.
Abstract:
In a patient with holoprosencephaly, partial seizures had various initial ictal symptoms, and ictal EEGs showed epileptogenic foci in the right and left brain. Partial seizures did not culminate in secondary generalized tonic-clonic convulsions. Characteristic malformed structures contribute to the absence of secondary generalization and the presence of Jacksonian-type propagation.
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