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Identification and quantitation of sodium-thyroxine and its degradation products by LC using electrochemical and MS

A G Kazemifard1, D E Moore, A Aghazadeh

  • 1College of Pharmacy, Medical Sciences University of Tehran, Tehran, Iran. kazemifa@sina.tums.ac.ir

Journal of Pharmaceutical and Biomedical Analysis
|May 30, 2001
PubMed

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The role of the detectors in High-Performance Liquid Chromatography (HPLC) is to analyze the solutes as they exit from the chromatographic column. The detector recognizes the solute's property and generates corresponding electrical signals, which are converted into a readable graph of the detector's response versus elution time called a chromatogram at the computer. There are several types of HPLC detectors, each with its own advantages and limitations, depending on the analyte properties and...