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Broadcast interference - functional genomics
1School of Biology, University of Leeds, Leeds, UK LS2 9JT. i.a.hope@leeds.ac.uk
Trends in Genetics : TIG
|May 30, 2001
Abstract:
Four recent papers mark a major shift in functional genomic analysis for multicellular organisms. RNA-mediated interference was applied to inactivate individual genes systematically on a genomic scale. These studies subjected a third of the genes in the genome of Caenorhabditis elegans to reverse genetic analysis.