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Functionally relevant polymorphisms in the human nuclear vitamin D receptor gene

G K Whitfield1, L S Remus, P W Jurutka

  • 1Department of Biochemistry, College of Medicine, 1501 N. Campbell Ave., University of Arizona, Tucson, AZ 85724, USA.

Molecular and Cellular Endocrinology
|May 30, 2001
PubMed
Summary

Two common human vitamin D receptor (hVDR) gene variations significantly impact its activity. Simultaneous analysis of these polymorphisms reveals distinct high and low activity groups, suggesting a third genetic factor.

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