Thromboembolism in heart failure, old ideas and new challenges
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Updated: Oct 7, 2026

In Vitro Microfluidic Disease Model to Study Whole Blood-Endothelial Interactions and Blood Clot Dynamics in Real-Time
Published on: May 24, 2020
1Cardiology Department, Hôpital Pitié-Salpêtrière, 47 Boulevard de l'Hôpital, 75651 Cedex 13, Paris, France. richard.isnard@psl.ap-hop-paris.fr
Abstract:
Until now, the administration of antithrombotic therapy in patients with congestive heart failure has not been well codified. The incidence of thromboembolic complication, such as stroke, peripheral or pulmonary embolism, is regarded as too low to justify the use of anticoagulation in non-selected patients. However, other thrombotic complications may occur especially in patients with ischemic heart failure and represent potential targets for antithrombotic therapy. The objective of this paper is to review the available evidence in the absence of the results of large ongoing trials.
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