Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Metabolic engineering as an integrating platform for strain development.

D E Stafford1, G Stephanopoulos

  • 1Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

Current Opinion in Microbiology
|May 30, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Improving CRISPR/Cas9-mediated genome editing efficiency in Yarrowia lipolytica using direct tRNA-sgRNA fusions.

Metabolic engineering·2020
Same author

Eliciting the impacts of cellular noise on metabolic trade-offs by quantitative mass imaging.

Nature communications·2019
Same author

Engineering Microbes to Synthesize Plant Isoprenoids.

Methods in enzymology·2016
Same author

Origins of Cell-to-Cell Bioprocessing Diversity and Implications of the Extracellular Environment Revealed at the Single-Cell Level.

Scientific reports·2015
Same author

Closed loop control for restoration of movement in paralyzed muscle.

Orthopedics·2014
Same author

Metabolic pathway alterations that support cell proliferation.

Cold Spring Harbor symposia on quantitative biology·2012
Same journal

The role of the antimicrobial peptide nisin as a clean label food preservative.

Current opinion in microbiology·2026
Same journal

From coarse-grained metabolic rules to fine-grained control of microbial communities.

Current opinion in microbiology·2026
Same journal

Progress in engineered bacterial cancer therapies.

Current opinion in microbiology·2026
Same journal

Constraints on adaptive loss-of-function mutations during microbial metabolic interactions.

Current opinion in microbiology·2026
Same journal

Discovery of novel antimicrobials within microbiomes.

Current opinion in microbiology·2026
Same journal

Beyond the protein lattice: bacterial S-layer glycans - from structure to functional frontier.

Current opinion in microbiology·2026
See all related articles

Metabolic engineering combines analytical tools with new technologies like DNA microarrays and directed evolution for better strain improvement and biocatalyst design. Advances in genomics and renewable resource use are driving metabolic engineering

Area of Science:

  • Biotechnology
  • Metabolic Engineering
  • Synthetic Biology

Background:

  • Metabolic engineering integrates analytical frameworks and experimental tools.
  • Emerging technologies like DNA microarrays and directed evolution are advancing the field.
  • Genomics and applied molecular biology have progressed significantly.

Purpose of the Study:

  • To highlight the integration of metabolic engineering with emerging technologies.
  • To emphasize the future improvements in strain improvement and biocatalyst design.
  • To underscore the growing importance of metabolic engineering in biotechnology.

Main Methods:

  • Analytical framework of metabolic engineering.
  • Experimental tools in metabolic engineering.

Related Experiment Videos

  • Application of emerging technologies (DNA microarrays, directed evolution).
  • Main Results:

    • Dramatic improvement in strain improvement approaches.
    • Enhanced biocatalyst design capabilities.
    • Advancement of metabolic engineering to the forefront of biotechnological interest.

    Conclusions:

    • The integration of metabolic engineering with new technologies will revolutionize strain improvement and biocatalyst design.
    • Progress in genomics and molecular biology supports this advancement.
    • The increasing focus on renewable resources fuels the rise of metabolic engineering.