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Kidney function after left renal vein ligation in the dog
G V Diniz1, W J Pereira, A C Moreira
1Laboratory of Experimental Surgery, Faculty of Medical Sciences, Minas Gerais.
Revista Do Hospital Das Clinicas
|May 30, 2001
Summary
Ligating the left renal vein can cause kidney damage. Tributaries are insufficient to maintain left kidney vitality and function after main vein ligature, leading to nephrosclerosis and necrosis.
Area of Science:
- Urology
- Nephrology
- Surgical Pathology
Background:
- The left renal vein may be ligated when injured.
- Understanding the collateral circulation's capacity is crucial for kidney preservation.
Purpose of the Study:
- To assess the sufficiency of left renal vein tributaries in maintaining left kidney vitality and function post-ligation.
Main Methods:
- Mongrel male dogs underwent left renal vein ligation (Group II) or ligation with right nephrectomy (Group III).
- Renal function was monitored via blood urea nitrogen and serum creatinine.
- Histological examination and imaging (arteriography, urogram) were performed.
Main Results:
- All Group III dogs (ligation + nephrectomy) died within two months, exhibiting kidney necrosis and hemorrhage.
- Group II dogs (ligation only) survived but showed signs of nephrosclerosis and loss of renal cortico-medullary definition.
- Left kidney exclusion was observed in all ligated animals.
Conclusions:
- The tributaries of the left renal vein are inadequate to sustain left kidney tissue vitality and function after main vein ligature.
- Renal vein ligation, especially with contralateral nephrectomy, poses significant risks to kidney viability.