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Update on nonallergic rhinitis
1Brown University School of Medicine, Providence, RI, USA. setti5@aol.com
Summary
Nonallergic rhinitis affects millions of Americans, with millions more experiencing mixed rhinitis. Effective treatments include azelastine and topical nasal steroids for this common condition.
Area of Science:
- Otolaryngology
- Allergology
- Immunology
Background:
- Nonallergic rhinitis is a recognized condition with limited prior study on its incidence and treatment.
- Recent research has improved understanding of nonallergic rhinitis prevalence and effective therapies.
Purpose of the Study:
- To review current knowledge on the incidence, significance, and therapy of chronic nonallergic rhinitis.
- To propose a classification for nonallergic rhinitis based on recent data.
Main Methods:
- Literature review of the MEDLINE database.
- Analysis of a national survey of allergists (National Rhinitis Task Force) across 15 practices and 975 patients.
Main Results:
- Nonallergic rhinitis likely affects up to 17 million Americans.
- Approximately 22 million Americans may have mixed rhinitis (nonallergic rhinitis with allergic diseases).
- Nonallergic and mixed rhinitis are more prevalent in adults, females, and as perennial conditions.
Conclusions:
- Nonallergic rhinitis is a common disorder with significant public health implications.
- Azelastine and topical nasal steroids are FDA-approved and effective treatments for nonallergic rhinitis.
- Further classification and understanding of nonallergic rhinitis are warranted.