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Update on nonallergic rhinitis.

R A Settipane1, P Lieberman

  • 1Brown University School of Medicine, Providence, RI, USA. setti5@aol.com

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
|May 31, 2001
PubMed
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Nonallergic rhinitis affects millions of Americans, with millions more experiencing mixed rhinitis. Effective treatments include azelastine and topical nasal steroids for this common condition.

Area of Science:

  • Otolaryngology
  • Allergology
  • Immunology

Background:

  • Nonallergic rhinitis is a recognized condition with limited prior study on its incidence and treatment.
  • Recent research has improved understanding of nonallergic rhinitis prevalence and effective therapies.

Purpose of the Study:

  • To review current knowledge on the incidence, significance, and therapy of chronic nonallergic rhinitis.
  • To propose a classification for nonallergic rhinitis based on recent data.

Main Methods:

  • Literature review of the MEDLINE database.
  • Analysis of a national survey of allergists (National Rhinitis Task Force) across 15 practices and 975 patients.

Main Results:

  • Nonallergic rhinitis likely affects up to 17 million Americans.

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  • Approximately 22 million Americans may have mixed rhinitis (nonallergic rhinitis with allergic diseases).
  • Nonallergic and mixed rhinitis are more prevalent in adults, females, and as perennial conditions.

    • Conclusions:

    • Nonallergic rhinitis is a common disorder with significant public health implications.
    • Azelastine and topical nasal steroids are FDA-approved and effective treatments for nonallergic rhinitis.
    • Further classification and understanding of nonallergic rhinitis are warranted.