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Gastric emptying and electrogastrography in patients on CAPD
A Fernström1, B Hylander, P Grybäck
1Department of Internal Medicine, Karolinska Hospital, Stockholm, Sweden.
Summary
Gastric emptying is slower in male continuous ambulatory peritoneal dialysis (CAPD) patients. However, electrogastrographic abnormalities do not explain this impaired gastric emptying in CAPD patients.
Area of Science:
- Nephrology
- Gastroenterology
- Medical Imaging
Background:
- Disturbed eating behavior is common in patients undergoing continuous ambulatory peritoneal dialysis (CAPD).
- The role of impaired gastric emptying in this eating behavior requires further investigation.
- Electrogastrography (EGG) assesses gastric myoelectric activity, which may be altered in dialysis patients.
Purpose of the Study:
- To determine if impaired gastric emptying of solids contributes to disturbed eating behavior in CAPD patients.
- To investigate the association between impaired gastric emptying and electrogastrographic (EGG) abnormalities in predialytic and dialytic patients.
Main Methods:
- A cross-sectional study involving 30 CAPD outpatients and 160 healthy controls.
- Gastric emptying was assessed using 99mTc-labeled test meals and scintigraphy over 2 hours.
- Simultaneous cutaneous electrogastrography (EGG) recorded gastric myoelectric activity.
Main Results:
- Male CAPD patients exhibited prolonged half-emptying time (T50), increased gastric retention (Ret 90/120), and slower gastric emptying rate (GER) compared to male controls.
- No significant differences in postprandial electrogastrography (EGG) were observed between CAPD patients and controls.
Conclusions:
- Gastric emptying is impaired in male, non-diabetic CAPD patients.
- Electrogastrographic abnormalities do not appear to explain the impaired gastric emptying observed in these patients.