Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Review article: the therapy of constipation.

L R Schiller1

  • 1Baylor University Medical Center, Dallas, Texas 75246, USA. LRSMD@aol.com

Alimentary Pharmacology & Therapeutics
|May 31, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Virtual colonoscopy: ready for prime time.

Current gastroenterology reports·2001
Same author

Constipation and fecal incontinence in the elderly.

Gastroenterology clinics of North America·2001
Same author

Diarrhea.

The Medical clinics of North America·2000
Same author

Secretory diarrhea.

Current gastroenterology reports·2000
Same author

Pathophysiology and treatment of microscopic-colitis syndrome.

Lancet (London, England)·2000
Same author

Microscopic colitis syndrome: lymphocytic colitis and collagenous colitis.

Seminars in gastrointestinal disease·1999

Constipation, a common condition, can be treated with laxatives that add bulk, retain water, or stimulate the bowels. New drugs targeting gut motility and other therapies like biofeedback and surgery are also available.

Area of Science:

  • Gastroenterology
  • Pharmacology

Background:

  • Constipation is a prevalent symptom with diverse etiologies, ranging from idiopathic cases to identifiable diseases.
  • Current treatments include laxatives, which function by adding bulk, osmotic water retention, or stimulating intestinal secretion/motility.
  • Other therapeutic options such as biofeedback and surgical interventions are also employed.

Purpose of the Study:

  • To review the mechanisms of action and applications of various constipation treatments.
  • To highlight emerging therapeutic strategies for managing constipation.
  • To discuss the role of laxatives and lavage solutions in bowel preparation and evacuation.

Main Methods:

  • Literature review of existing studies on constipation and its treatments.
  • Analysis of pharmacological mechanisms of laxatives and novel drug development.

Related Experiment Videos

  • Examination of non-pharmacological interventions like biofeedback and surgery.

    • Main Results:

    • Laxatives are categorized by their effects: bulking agents, osmotic agents, and stimulants.
    • Novel pharmacologic agents targeting gastrointestinal motility are under investigation.
    • Biofeedback and surgery represent alternative or adjunctive treatment modalities.

    Conclusions:

    • A range of therapeutic options exist for constipation, with ongoing development in pharmacologic interventions.
    • Laxatives remain a cornerstone treatment, with specific agents chosen based on mechanism and patient needs.
    • Comprehensive management may involve a combination of pharmacological and non-pharmacological approaches.