Related Experiment Video

Updated: Aug 7, 2026

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
10:22

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

Transient oromotor deficits in children with benign childhood epilepsy with central temporal spikes

U Kramer1, B Ben-Zeev, S Harel

  • 1Child Developmental Center & Pediatric Neurology Unit, Tel Aviv Sourasky Medical Center, Israel. umkramer@netvision.net.il

Epilepsia
|June 1, 2001
PubMed

Insights

Transient oromotor deficits, like dysarthria and drooling, can occur in benign childhood epilepsy with centrotemporal spikes (BCECTS) and are linked to increased seizure activity.

Area of Science:

  • Pediatric Neurology
  • Epileptology
  • Clinical Neurophysiology

Background:

  • Benign childhood epilepsy with centrotemporal spikes (BCECTS) is an idiopathic, age-specific epileptic syndrome known for its generally benign course.
  • Oromotor deficits are not typically considered a primary feature of BCECTS, making their presentation noteworthy.

Observation:

  • This study presents five children with BCECTS experiencing intermittent dysarthria and drooling outside of typical clinical seizure manifestations.
  • These oromotor deficits were observed to correlate with increased seizure frequency in all affected children.

Findings:

  • Electroencephalograms (EEGs) conducted during episodes of dysarthria in four children revealed focal electrographic seizures, confirming an ictal origin.
  • The children presenting with these transient oromotor symptoms did not exhibit other distinguishing clinical features compared to typical BCECTS patients.

Implications:

  • Transient oromotor dysfunction represents a rare ictal phenomenon in BCECTS, potentially indicating subclinical seizure activity.
  • Recognizing these deficits as a rare ictal manifestation can aid in accurate diagnosis and management of BCECTS in children.
  • This finding underscores the importance of considering ictal phenomena beyond overt motor seizures in pediatric epilepsy syndromes.
Abstract

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