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Updated: Aug 24, 2026
Rapid Lipid Droplet Isolation Protocol Using a Well-established Organelle Isolation Kit
Published on: April 19, 2019
[LDL-apheresis: current status]
C Stefanutti1, A Vivenzio, G Lucani
1Sezione di Plasmaferesi Terapeutica, Istituto di Terapia Medica Sistematica, Policlinico Umberto I, Università degli Studi di Roma La Sapienza, Roma, Italia. plasmaferesi@tin.it
Purpose:
State of the art of LDL-apheresis and treatment of severe familiar hypercholesterolemia.
Patients And Methods:
Clinical experience of treatment with LDL-apheresis of pediatric and adult patients with familial hypercholesterolemia using the following techniques: D.A.L.I., H.E.L.P., D.S.C.
Results:
The outcome of treatment with LDL-apheresis in young patients, using the most recently introduced techniques, is reported. We have submitted to LDL-apheresis 11 pediatric patients. The youngest is aged 3.5. LDL-apheresis is able at improving the metabolic impairment and halting the natural evolution of atherosclerotic disease and atherosclerotic complications.
Conclusions:
At present, LDL-apheresis is the most effective and safe therapeutic approach to the treatment of homozygous, heterozygous and double heterozygous familial hypercholesterolemia.
