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Long-term treatment with idebenone and riboflavin in a patient with MELAS
A Napolitano1, S Salvetti, M Vista
1Division of Neurology, Campo di Marte Hospital, I-55100 Lucca, Italy.
Abstract:
We report a patient with MELAS treated for 24 months with idebenone and riboflavin, during which no stroke-like episodes occurred. Moreover neurological symptoms clearly improved, and a recovery of brain MRI and EEG abnormalities was observed. We conclude that the combined treatment with idebenone and riboflavin may restore the metabolic impairment in MELAS, possibly improving the long-term prognosis in these patients.